Safety Alert: Ibuprofen May NOT Be Safe to Use for Pain Relief During COVID-19 Outbreak

*Disclaimer: The information in this article is our best opinion on the current research on COVID-19. It is NOT medical advice or intended in any way to be a substitute for medical advice. The information provided is not intended to treat, diagnose, cure or prevent any condition or disease including corona virus (COVID-19). This is merely a presentation of our own research and we could be WRONG. Please do not discontinue any prescribed medications without the express direction of you medical doctor. Please use extreme caution when assessing info about this virus and please consult your licensed medical providers for treatment options. This article has not been validated or reviewed by the FDA.*


A warning was recently issued by the government of France via Olivier Veran, the French Health Minister: COVID-19 infected patients should NOT take nonsteroidal anti-infammatory drugs (NSAIDS) such as Advil and ibuprofen. Based on their experience, they believed that NSAID usage may increase the virulence of COVID-19 infections, making them much worse.(1) He went as far as to state that “NSAIDS should be banned.”

Although the U.S. National Institute for Allergy and Infectious Diseases has stated that “more research is needed to evaluate reports that ibuprofen and other over-the-counter anti-inflammatory drugs may affect the course of COVID-19,” there are two serious scientific reasons to err on the side of caution and steer clear of NSAID use during this coronavirus outbreak.(2)

Scientific reason #1: Ibuprofen May Increase Amount of ACE2 Receptors

COVID-19 has been shown to use an receptor known as Angiotensin-Converting Enzyme 2 (ACE2) to enter the cell and replicate.(3) Lab studies have shown that ibuprofen may boost the amount of ACE2 receptors the virus uses to infect cells, thus making the virus spread faster.

Dr. Carlos Del Rio, professor of medicine and global health in the division of infectious disease at Emory University stated in a Review COVID-19 Update on Early Safety Signals Around Ibuprofen and Renin-Angiotensin Inhibitors that, “medications which up-regulate ACE may lead to worsening and bad outcomes...this medication may include ibuprofen as well as ACE inhibitors and angiotensin blockers.” Dr. Del Rio also mentioned that the WHO had alerted the medical community “to avoid ibuprofen in suspected or confirmed cases of COVID-19…” (4). The WHO has since adopted a more neutral position citing the need for further research, but we believe erring on the side of caution is more prudent in this situation. 

Dr. Del Rio further noted that the ACE2 receptor, through which the virus actually enters the cells, is present in large numbers in the lung cells. As we have explained in our previous article, the Prevotella bacteria that the COVID-19 virus is infecting is also present in the largest quantities in the lungs. 

Studies have shown that the use of ibuprofen (NSAIDS) INCREASES the amount of Prevotella in the microbiome(5). Please read our latest article, to understand the critical link between the abundance of Prevotella in the microbiome and the potential virulence of the COVID-19 virus. 

Scientific Reason #2: Ibuprofen May Dampen the Immune Response

A doctor from the National Health Services (NHS), Dr. Amir Khan, explained the potential harm that may be cause by the use of ibuprofen, stating that: 

“We need these inflammatory chemicals to help tackle the virus in the medium to long term. It is the effectiveness of these chemicals that decides whether a person develops complications from the coronavirus or makes a full recovery. If we take medicines that dampen this immune response, such as ibuprofen, this can lead to us not fighting off the infection as effectively, potentially leading to a longer illness with a higher risk of complications.” (6)

Better Natural Pain Relief Alternatives 

Many natural remedies can powerfully relieve pain while also boosting immunity, which is critical in the time of this coronavirus outbreak. 

Plum Dragon’s topical, herbal analgesics (called Dit Da Jow in Chinese Medicine) are among the most powerful natural pain-relievers on the planet. The herbs in these formulations work synergistically with the body to help facilitate the body’s natural healing processes and provide natural pain relief. 

If you want the in depth explanation for why these formulas work so well, read this article. 

If you want the quick overview of Dit Da Jow, click here

If you just want to know which formula/s you should use right now for pain relief, keep reading :)

Which formula should I use?

If you are new to the world of Dit Da Jow, there are three main formulas for natural pain relief and recovery from injury. All of these formulas are great for your body and work with your body to preserve the integrity of the immune system functions as well as to powerfully relieve pain and help your body heal itself. 

Bruise Juice

This formula is best for fresh injuries with visible bruising, redness and swelling. This is a strong anti-inflammatory and can be used for all kinds of inflammation and pain connected with a fresh injury, bruise, welt, sprain or strain.

    The Ho Family Dit Da Jow

    This choice is best for all other injuries that have moved beyond the bruising/inflammation stage. This is the best choice for general pain management, muscle injuries, tendonitis, and pain from post-surgical/post-trauma recovery, including nerve pain.

      Ancestors Advanced Dit Da Jow

      This formula is best for arthritic pain and pain associated with other degenerative conditions. It is also best for very old injuries that have not been able to heal properly.




      More Ideas for Natural Pain Relief

      Along with these topical medicines, there are several pain-relieving remedies and techniques you can add to your natural pain relief regimen: 

      Meditation/Breathing Exercises


      Proper Hydration

      Moderate exercise - especially walking and yoga!

      Omega-3 from high quality fish oil

      Adequate exposure of skin to sunlight




      Stay safe and be well!



      5. Rogers MAM, Aronoff DM. The influence of non-steroidal anti-inflammatory drugs on the gut microbiome. Clin Microbiol Infect. 2016;22(2):178.e1–178.e9. doi:10.1016/j.cmi.2015.10.003

      1 comment

      UPDATE (May 28th, 2020): It is dangerous to discourage people from taking NSAIDS in general because aspirin is the only effective antipyretic for covid-19 and is the standard for treating children with Covid-19 who develop Multisystem Inflammatory Syndrome. None of the formulations you offer lower fever. Feverfew, willow bark, and even a warm foot bath lower fever.

      If you learned how to keep your hands to yourself and stopped sticking needles into small animals you would know that.

      L June 01, 2020

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